The MSC: An Injury Drugstore

Underwater Drugstore

the CENR prepared preliminary strategies for establishing scientific approaches and short-term priorities for seven programmatic and three cross-cutting issue areas in which to address the administration's concerns about federal R&D efforts. The programmatic issues include air quality, biodiversity and ecosystems, global change, natural disasters, resource use and management, toxic substances a...

Revolution at the Corner Drugstore

An expanding armamentarium of oral oncologic drugs represents a revolution in the treatment of cancer but also presents significant challenges to adherence and the management of costs, side effects, and a growing clinician workload. Most often, identifying the urgent needs of cancer patients, including financial support and education, falls to the health care giver, whichincludes advanced pract...

The decline and fall of the neighborhood drugstore.

Is the drugstore safe? Counterfeit diabetes products on the shelves.

It is no longer possible to identify counterfeit medical products, including medications and devices, by simply checking packaging and labeling. Improvements in technology have made it cheaper and easier to produce fake packaging and labels, making it nearly impossible for consumers and authorities to detect counterfeits without conducting tests on the products themselves, as illustrated by the...

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury.

Human ESC-derived mesenchymal stem cell (MSC)-conditioned medium (CM) was previously shown to mediate cardioprotection during myocardial ischemia/reperfusion injury through large complexes of 50-100 nm. Here we show that these MSCs secreted 50- to 100-nm particles. These particles could be visualized by electron microscopy and were shown to be phospholipid vesicles consisting of cholesterol, sp...